Method of preparing .alpha.-l-aspartyl-l-phenylalanine methyl es

Details Method of preparing .alpha.-l-aspartyl-l-phenylalanine methyl es Method of preparing .alpha.-l-aspartyl-l-phenylalanine methyl es

1992-05-21

1994-03-08

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 41, 562450, C07C22900

Patent

active

052929230

ABSTRACT:
A method of preparing .varies.-L-aspartyl-L-phenylalanine methyl ester hydrochloride (.varies.-APM.HCL) from a reaction mixture of N-formyl-L-aspartic acid anhydride and L-phenylalanine methyl ester (PM), wherein .alpha.-APM.HCl is produced without isolating an intermediate by solid-liquid separation during the course of the reaction process.

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patent: 4778916 (1988-10-01), Mita et al.
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