Method of preparing a radioactive rhenium complex solution

Details Method of preparing a radioactive rhenium complex solution Method of preparing a radioactive rhenium complex solution

2006-03-28

2006-03-28

Geist, Gary (Department: 1623)

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

C534S010000, C534S014000

Reexamination Certificate

active

07018612

ABSTRACT:
The invention relates to a method of preparing a solution of a radioactive rhenium complex, by reacting at elevated temperature a radioactive perrhenate in a substantially aqueous solution with a ligand in the presence of a reductant and optionally an antioxidant under substantially anaerobic conditions, wherein said reaction is carried out at a pH from approx. 1.5 to approx. 5 and by heating the reaction components for at least 10 min. at a temperature of at least 100° C. The invention further relates to a kit for performing said method.

REFERENCES:
patent: 4451450 (1984-05-01), Subramanyam
patent: 4455291 (1984-06-01), Tweedle
patent: 4935222 (1990-06-01), Deutsch et al.
patent: 5192526 (1993-03-01), Pipes
Concise Encyclopedia Chemistry, 1994, p. 107.
Mortimer,Chemistry, A Conceptual Approach, 1979, p. 471.

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