Method of preparing a purified glucosyltransferase

Details Method of preparing a purified glucosyltransferase Method of preparing a purified glucosyltransferase

1979-12-14

1981-02-10

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

435815, 435885, C12N 910

Patent

active

042502624

ABSTRACT:
Immunization of animals with preparations containing more purified forms of glucosyltransferase (GTF) results in the presence of antibody in saliva demonstrable by functional inhibitions of enzyme activity and binding of radioactive enzyme. Serum antibody was also present. Immunized groups of animals had lower mean caries scores than comparably sham-immunized or nonimmunized control groups. Local immunization with GTF of serotype c or g of a Streptococcus mutans reduces the colonization, caries, and lesions caused by infection with S. mutans of serotype g (strain 6715) or c, or with serotype g or c, or with serotype a or g, respectively.

REFERENCES:
patent: 3993747 (1976-11-01), Gaffar et al.
Taubman et al., The Journal of Immunology, vol. 118, No. 2, pp. 710-720 (Feb. 1977).
Guggenheim et al., Dental Plaque, pp. 287-296 (1970) McHugh ed., Dundee, Scotland.

Affiliated with

Also associated with

Rating

Method of preparing a purified glucosyltransferase does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of preparing a purified glucosyltransferase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of preparing a purified glucosyltransferase will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1665993