Method of preparing a cryoprecipitated suspension and use thereo

Details Method of preparing a cryoprecipitated suspension and use thereo Method of preparing a cryoprecipitated suspension and use thereo

1988-06-06

1990-05-29

Morris, Theodore

Compositions: coating or plastic

Coating or plastic compositions

Proteinaceous material containing

106161, 128334R, 424 28, 424530, 514 2, 514802, A61B 1704, A61K 3700, C08L 8900

Patent

active

049286030

ABSTRACT:
This invention concerns a method of preparing a cryoprecipitated suspension containing fibrinogen and Factor XIII useful as a precursor in the preparation of a fibrin glue which involves (a) freezing fresh frozen plasma from a single donor such as a human or other animal, e.g., a cow, sheep or pig, which has been screened for blood transmitted diseases, e.g., one or more of syphilis, hepatitis or acquired immune deficiency syndrome at about -80.degree. C. for at least 6 hours, preferably for at least about 12 hours; (b) raising the temperature, so as to form a supernatant and a cryoprecipitated suspension containing fibrinogen and Factor XIII; and (c) recovering the cryopricipitated suspension.

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