Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice
Reexamination Certificate
1999-06-22
2001-07-10
Jones, Dameron L. (Department: 1616)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Cosmetic, antiperspirant, dentifrice
C424S400000, C424S059000
Reexamination Certificate
active
06258366
ABSTRACT:
The present invention concerns a method of preparing a product intended for cutaneous protection against attack resulting from pollution of the ambient air and a method of protecting the skin against such attack.
Human beings are subjected daily to ever increasing pollution. Changes in the ecosystem, reinforced by over-population and excessive human activity, cause high pollution levels. This situation was largely generated initially by our industrial activity. There has been a change in the environment itself, with a reduction in the stratospheric ozone layer, an intensified greenhouse effect giving rise to global warming. The triposhere is gradually becoming an oxiding medium (O
3
, NOx, metals).
To all this it is necessary to add cigarette fumes which impinge on facial skin. These cause a reduction in hydration and oxygenation.
The mechanisms by which pollution and its effects act on the skin remain poorly known. It is known however that tobacco causes right-angled wrinkles at the edge of the lips, numerous furrows on the checks and chin an a greyish complexion.
In addition, urban pollution causes acidification of the skin, disturbance of hydration with a concomitant increase in the transepidermal water loss, an increase in skin flaking and a reduction in skin flexibility.
As a protective barrier between the body and the external environment, it is the skin which is confronted with the harmful effects of pollution.
The purpose of the invention is to propose a method of protecting the skin which considerably reduces the effect of this pollution on the skin.
To do this, a method according to the invention consists of using the product of the enzymatic depolymerisation of a sodium alginate extracted from an alga, for example a brown alga. The alginate in question is a linear copolymer consisting of sodium &agr;-L-guluronate and sodium &bgr;-D-mannuronate bonded at positions 1,4 in homogeneous alternating blocks. For this enzymatic depolymerisation, an enzyme of the mannuronate lyase type, preferably an alginate lyase, has, for example, been used.
This enzyme, obtained by bacterial fermentation, makes it possible to depolymerise, by &bgr;-elimination, the alternating blocks of the sodium alginate molecule. In addition, the aforementioned enzyme very quickly reduces the viscosity of the sodium alginate solution at the end of said depolymerisation step.
For example, the product used is prepared as follows. The alga extract consisting of sodium alginate is first of all solubilised for one hour at a concentration of 5%. The solubilised alginate extract is then subjected to an enzymatic depolymerisation at a temperature of 25° C. for four hours, by means of a lyase alginate known as AL 951. In addition, the ratio by weight of enzyme to alginate is 0.01% and the pH of the mediums is 7.5.
The oligoalginates obtained by this depolymerisation are formed by the linking of two uric acids: mannuronic acid and guluronic acid.
The said degree of polymerisation of the product used is advantageously 80, measured by the so-called “conjugated double bond determination” method. The mean molecular weight in number is approximately twenty thousand daltons, measured by the so-called “reducing sugars determination” method of Somogyi-Nelson.
The present invention also concerns a method for producing a cosmetic product intended for protecting the skin against pollution attack. It is characterised in that it also was an enzymatic depolymerisation product of a sodium alginate extracted from an alga of the type described above.
REFERENCES:
patent: 5416205 (1995-05-01), della Valle et al.
patent: 5776445 (1995-07-01), Cohen et al.
patent: 18 07 152 (1970-05-01), None
patent: 30 17 221 (1980-11-01), None
patent: 1 345 295 (1964-03-01), None
Patent Abstracts of Japan, vol. 10, No. 262 (C-371) [2318], Sep. 6, 1986, & JP 61 087614 A (Daiichi Seimo), May 6, 1986.
Gedouin Antoine
Vallee Romuald
Codif International S.A.
Jones Dameron L.
Lowe Hauptman Gilman & Berner
LandOfFree
Method of preparing a cosmetic product intending to protect... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of preparing a cosmetic product intending to protect..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of preparing a cosmetic product intending to protect... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2565263