Method of preparing a copolymer of two .alpha.-amino acids and a

Details Method of preparing a copolymer of two .alpha.-amino acids and a Method of preparing a copolymer of two .alpha.-amino acids and a

1991-02-15

1992-08-04

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

523111, 528313, A61F 1300

Patent

active

051357542

ABSTRACT:
The invention provides a method of synthesizing a copolymer of two .alpha.-amino acids which comprises the preparation of an N-carboxyanhydride of a first .alpha.-amino acid and the N-carboxyanhydride of a second .alpha.-amino acid, followed by the copolymerization of this mixture. The mixture is obtained by the reaction of phosgene with a mixture of a first and the second .alpha.-amino acids, the amino acids having similar reaction rates with phosgene. It also relates to the copolymer obtained by implementation of this method and an agent for covering skin wounds comprising this copolymer.

REFERENCES:
patent: 2699391 (1955-01-01), Mueller
patent: 2993053 (1961-07-01), Ballard
patent: 2996513 (1961-08-01), Ballard
patent: 3637727 (1972-01-01), Fujimoto et al.
patent: 3644412 (1972-02-01), Fujimoto et al.
patent: 3867520 (1975-02-01), Mori et al.
patent: 4125519 (1978-11-01), Goodman et al.
patent: 4161948 (1979-07-01), Bichon
patent: 4374134 (1983-02-01), Kocsis

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