Compositions – Preservative agents – Anti-corrosion
Patent
1976-01-26
1977-04-05
Lovering, Richard D.
Compositions
Preservative agents
Anti-corrosion
424 19, 424 36, 427 3, 427398B, B01J 1302, A61K 952
Patent
active
040161005
ABSTRACT:
A pharmaceutical composition is prepared by the steps of dispersing a phospholipid uniformly in water to give an aqueous phospholipid dispersion, adding a medicament to the aqueous dispersion, freezing the thus-obtained aqueous dispersion, thereby entrapping the medicament in the lipid spherules, and then thawing the frozen dispersion to give an aqueous suspension of the medicament entrapped in the lipid spherules having a diameter of less than 5.0 .mu.. The pharmaceutical composition prepared above is used as a controlled release pharmaceutical preparation.
REFERENCES:
patent: 3056728 (1962-10-01), Ohtaki
patent: 3780195 (1973-12-01), Balassa
Chemical Abstracts, vol. 81, 1974, p. 324, 96409m.
Matsuda Saburo
Miura Hiroshi
Ohsawa Takashi
Suzuki Akira
Lovering Richard D.
Tanabe Seiyaku Co. Ltd.
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