Method of preparation of lyophilized biological products

Details Method of preparation of lyophilized biological products Method of preparation of lyophilized biological products

1974-08-16

1976-01-20

Camby, John J.

Drying and gas or vapor contact with solids

Apparatus

With means to treat gas or vapor

F26B 506

Patent

active

039329437

ABSTRACT:
Disclosed herein is a homogeneous, lyophilized particulate product of a substance containing at least one biologically active component and a process for its preparation which involves forming a solution or colloidal suspension of the substance, spraying the solution or colloidal suspension into a moving bath of fluorocarbon refrigerant and lyophilizing the resultant frozen droplets. The porous product has a spherical shape, free-flowing properties, and rapid dissolution times.

REFERENCES:
patent: 2149304 (1939-03-01), Masucci
patent: 3228838 (1966-01-01), Rinfret et al.
patent: 3269025 (1966-08-01), Dryden et al.
patent: 3281950 (1966-11-01), Kautz
patent: 3607858 (1971-09-01), Querry et al.
patent: 3620776 (1971-11-01), Mishkin
patent: 3888017 (1975-06-01), McBride

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