Method of preparation of 5,6-dehydropenicillins

Details Method of preparation of 5,6-dehydropenicillins Method of preparation of 5,6-dehydropenicillins

1979-07-19

1981-09-08

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424270, 204158R, C07D49900

Patent

active

042883660

ABSTRACT:
A method is disclosed for the preparation of a class of dehydropenicillins by irradiating substituted 4-acylmethylthio-2-azetidinones and subsequently subjecting the as-obtained product to cyclization. Processing conditions and analytical data are reported.

REFERENCES:
patent: 4133807 (1979-01-01), Re et al.
patent: 4160091 (1979-07-01), Herron
patent: 4174318 (1979-11-01), Barton et al.
Justus Liebigs, Annalen der Chemie, 1974, Heft 9, pp. 1361 & 1937.
Yoshimote et al., Tetrahedron Letters, No. 43, pp.4387-4390 (1972).

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