Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2009-03-18
2011-12-13
Martinell, James (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007100
Reexamination Certificate
active
08076084
ABSTRACT:
A method of predicting metastatic potential, prognosis or overall survival of cancer patients is provided. The method utilizes reliable markers, HIF-1α, TWIST or Snail, to predict the probability of the metastatic potential, prognosis situation or overall survival of cancer patients. Moreover, the method provided by the present invention can reach relatively higher predictability of metastatic potential, prognosis situation or overall survival as compared with the current markers.
REFERENCES:
patent: 2009/0092596 (2009-04-01), Haley et al.
Muh-Hwa Yang et al., “Direct Regulation of TWIST by HIF-1α Promotes Metastasis”, Nature Cell Biology, vol. 10, No. 3, Mar. 2008, pp. 295-305.
Hogan & Lovells US LLP
Martinell James
National Yang-Ming University
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