Method of photometric in vitro determination of the content of a

Details Method of photometric in vitro determination of the content of a Method of photometric in vitro determination of the content of a

1994-02-22

1994-11-22

Housel, James C.

Chemistry: analytical and immunological testing

Optical result

With claimed manipulation of container to effect reaction or...

436 68, 436164, 422 8205, 422 8211, 128633, 356 39, 356246, 356434, G01N 2103

Patent

active

053669037

ABSTRACT:
A sampling device for photometric determination of the content of an analyte in a sample of whole blood has at least one measuring chamber having two wall parts, at least one wall part being locally transparent, at least one wall part being sufficiently deformable to facilitate displacement of the whole blood sample from the measuring chamber. The measuring chamber also contains a transparent body having a radiation transmission characteristic dependent upon the concentration of a predetermined analyte in the whole blood sample. The sample device is employed in an analyzer for photometric determination of the content of an analyte in a sample of whole blood and in a method of photometric in vitro determination of the content of an analyte in a sample of whole blood. In the method, a sample of whole blood is transferred directly from an in vivo locality to the sampling device, the measuring chamber therein is deformed in a controlled manner to substantially drain the whole blood from the measuring chamber, radiation is transmitted through the substantially drained measuring chamber, detected, and the analyte content determined.

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