Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-06-07
1998-06-09
Marschel, Ardin H.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
536 221, 536 231, 536 243, 536 2532, 514 1, 514 44, C12Q 168, C07H 1900, A01N 6100
Patent
active
057631727
ABSTRACT:
A method of phosphate ester hydrolysis including incubating a solution of an aqueous phosphate ester with a metallotexaphyrin complex under conditions and for a time sufficient to hydrolyze the phosphate ester. The metal is a metal cation having catalytic activity for ester bond hydrolysis in aqueous solution. Phosphate ester substrates include nucleic acid such as RNA, phosphoric anhydrides, phospholipids, and alkyl phosphate esters.
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Dow William C.
Magda Darren
Miller Richard A.
Sessler Jonathan L.
Wright Meredith
Board of Regents , The University of Texas System
Larson Jacqueline S.
Marschel Ardin H.
Pharmacyclics Inc.
Riley Jezia
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