Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving blood clotting factor
Patent
1989-08-11
1992-12-29
Naff, David M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving blood clotting factor
435 2, 435 23, 436 66, A01N 102, C12Q 137, C12Q 156, G01N 3372
Patent
active
051750872
ABSTRACT:
The present invention relates to an improved method for collecting blood. The present invention also relates to a method of collecting blood whereby tissue plasminogen, tissue plasminogen activator inhibitor and other serine proteases, serine protease inhibitors and components that are produced or destroyed through the action of serine proteases in collected blood are stabilized. In addition, the present invention provides a method for collecting blood that reduces the hemolysis (lysis of red blood cells). Using the blood collecting method of the present invention, reliable control plasmas can be manufactured.
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patent: 4780419 (1988-10-01), Uchida et al.
Ceresa, editor "Block and Graft Copolymerization", vol. 2 pp. 194-201 (1976).
Wiman et al., "Plasminogen Activator Release During Venous Stasis and Exercise as Determined by a New Specific Assay", Clin. Chem. Acta, vol. 127, pp. 279-288 (1983).
Chmielewska et al., "Evidence for a Rapid Inhibitor to Tissue Plasminogen Activator in Plasma", Thromb. Res., vol. 31, pp. 427-436 (1988).
Berne, et al., editor, Physiology, pp. 382-385 (1988).
Faulkner, W. R., edit. "Selected Methods for Small Clinical Chemistry Laboratory", Selected Methods of Clinical Chemistry, vol. 9, pp. 6-7 and 328).
Ranby Mats G.
Wiman Tor-Bjorn
Biopool International, Inc.
Naff David M.
Reardon Timothy J.
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