Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is organic
Patent
1993-10-29
1995-06-06
Saunders, David
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is organic
210656, 210661, 210723, 210807, 422 59, 436524, 436526, 436531, 436536, 436538, 436539, 436541, 436824, 530412, 530413, 530418, G01N 33544, G01N 33546, G01N 33551, G01N 33553
Patent
active
054222842
ABSTRACT:
Disclosed is a primary chromatographic support containing an immobilized flocculating agent for use as a separation media for a secondary support consisting of microparticles used in affinity separation and heterogeneous immunoassays. In a specific embodiment, a flocculating agent such as polyethyleneimine is immobilized on a chromatographic resin packed in a column. The column so formed is then used to trap microparticles having an affinity ligand or binder for the ligand affixed thereon. Such microparticles are used as a solid support for the affinity reaction involved in a variety of immunoassay formats.
REFERENCES:
patent: 4661408 (1987-04-01), Lau et al.
patent: 4935147 (1990-06-01), Ullman et al.
Chin Christopher L.
E. I. Du Pont de Nemours and Company
Saunders David
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