Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Cell membrane or cell surface is target
Reexamination Certificate
2000-09-06
2008-01-22
Schnizer, Richard (Department: 1635)
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Cell membrane or cell surface is target
C435S173700, C435S375000
Reexamination Certificate
active
07320885
ABSTRACT:
A method of perforating a membrane10is presented. The method comprises: bringing a membrane-denaturing substance into contact with or close proximity to at least a site of said membrane10, said substance inducing a membrane-denaturing reaction by a stimulus; providing said stimulus to said substance so as to denature said membrane10; perforating said membrane with a membrane-destroying member1. The stimulus is carried through said membrane-destroying member1. The present invention eliminates the influence of membrane-denaturing agent to the substance to be injected into the cell. The present invention also enables applying the stimulus locally, with a simple construction.
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Christensen O'Connor Johnson & Kindness PLLC
Schnizer Richard
Toudai TLO, Ltd.
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