Package making – Methods – With contents treating
Patent
1992-02-18
1993-02-09
Coan, James F.
Package making
Methods
With contents treating
53127, 53237, 53474, 53489, 604191, B65B 3104, B65B 728, B67C 300, A61M 519
Patent
active
051844508
ABSTRACT:
In a method of packaging freeze dried vaccine in a bypass syringe sterilized syringes are disposed in rows in an aseptic dispensing machine. Doses of a solution or suspension to be freeze dried are introduced into the syringes. A temporary plug is inserted in the same machine into the mouth of the syringe body in a position allowing communication between the interior of the syringe body and the exterior. The syringes are introduced into a freeze drying machine. The vaccine is freeze dried. At the end of the freeze drying cycle the temporary plug is depressed in a controlled atmosphere in the freeze drying machine into a hermetic sealing position. The syringes are transferred into an aseptic dispensing machine. The temporary plug is removed. An intermediate piston-plug is fitted. The dose of solvent is introduced and an end piston-plug is fitted.
REFERENCES:
patent: 3348546 (1967-10-01), Roberts et al.
patent: 4716710 (1988-01-01), Galy et al.
patent: 4792329 (1988-12-01), Schreuder
patent: 4874381 (1989-10-01), Vetter
patent: 4968299 (1990-11-01), Ahlstrand et al.
patent: 4994043 (1991-02-01), Ysebaert
Galy Michel G. H.
Gomez Alain
Coan James F.
Pasteur Merieux Serums et Vaccins
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