Package making – Methods – Forming a cover adjunct or application of a cover adjunct to...
Patent
1987-12-23
1989-02-21
Sipos, John
Package making
Methods
Forming a cover adjunct or application of a cover adjunct to...
53425, 53449, 53471, B65B 5502, B65B 728
Patent
active
048053775
ABSTRACT:
A method of filling, sealing and sterilizing a pharmaceutical package including a polypropylene bottle containing a balanced salt solution includes the steps of filling each bottle to maximum capacity to exclude residual air, the introduction of a silicone rubber gasket into the bottle cap to absorb pressure and prevent leakage during a steam sterilization procedure, and the enclosure of the filled bottles in a blister pack before stream sterilizing. The blister packs have Tyvek.TM. closures and are placed blister-side-up during the sterilization process to eliminate deformation of the blister during sterilization. Maximum filling of the bottle with liquid and the substantial elimination of air prevents dimpling of the bottle.
REFERENCES:
patent: 2004079 (1935-06-01), McManus
patent: 4467588 (1984-08-01), Carveth
Entravision, Inc.
Sipos John
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