Method of optical resolution of (.+-.)-2-amino-1-butanol and/or

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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562402, 564303, C07B 1900, C07C 8904

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active

043407510

ABSTRACT:
(.+-.)-2-Amino-1-butanol and/or (.+-.)-mandelic acid are optically resolved with a high resolution efficiency and high optical purities by preferentially crystallizing out one of the pair of less soluble enantiomeric salts (or optical antipodes), namely (+)-2-amino-1-butanol-(+)-mandelic acid salt and (-)-2-amino-1-butanol-(-)-mandelic acid salt.

REFERENCES:
patent: 3944617 (1976-03-01), Singh
patent: 4224239 (1980-09-01), Tashiro et al.
patent: 4239912 (1980-12-01), Halmos
patent: 4259521 (1981-03-01), Kazan et al.

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