Method of obtaining a splenic composition which inhibits platele

Details Method of obtaining a splenic composition which inhibits platele Method of obtaining a splenic composition which inhibits platele

1976-05-20

1978-05-09

Rosen, Sam

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

A61K 3528

Patent

active

040887537

ABSTRACT:
A process is provided for extracting and isolating a material from a spleen which is capable of inhibiting platelet function. It has been found that such material is capable of lowering platelet count or fibrinogen concentration or both. The process includes the steps of subjecting the spleen to a polar solvent and subjecting the filtrate to a chromatography process to obtain certain R.sub.f values.

REFERENCES:
patent: 2616826 (1952-11-01), Moolten
patent: 2662047 (1953-12-01), Amozurrutia
patent: 2987443 (1961-06-01), Littman et al.
Steiman et al.-Chem. Abst. vol. 75, (1971), p. 116,538j.

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