Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1994-06-21
1996-12-31
Hutzell, Paula K.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 794, 435961, 435967, 436 86, 436174, 436501, 436518, 436811, 436813, 436815, G01N 33543
Patent
active
055893465
ABSTRACT:
A method of monitoring markers of bone metabolism by continuously collecting a body fluid sample containing bone loss markers therein and analyzing the components of the body fluids for the markers of bone metabolism.
REFERENCES:
patent: 4957108 (1990-09-01), Schoendorfer et al.
patent: 4973666 (1990-11-01), Eyre
patent: 5076273 (1991-12-01), Schoendorfer et al.
patent: 5140103 (1992-08-01), Eyre
patent: 5203327 (1993-04-01), Schoendorfer et al.
patent: 5283197 (1994-02-01), Robins
Schlemmer et al., "Marked diurnal variation in urinary excretion of pyridinium cross-links in premenopausal women" J. Clin. Endocrin Metab., 74:476-80 (1992).
Eastell et al., "Nycthoemeral changes in bone turnover assessed by serum bone gla-protein concentration and urinary deoxypyridinoline . . . " Clin. Sci., 83:375-82 (1992).
Eastell et al., "Abnormalities in circadian patterns of bone resorption . . . " J. Clin. Endocrin Metab., 74:487-94 (1992).
Gertz et al., "Monitoring bone resorption in early postmenopausal women . . . " J. Bone Min. Res., 9:135-142 (1994).
Bettica et al., "Bone-resorption markers galactosyl hydroxylsine, pyridinium . . . " Clin. Chem. 38:2313-8 (1992).
Delmas, PD., "Biochemical markers of bone turnover: methodology and clinical use in osteoporosis" Am. J. Med., 91(Supp 5B):59S-63S (1991).
Harvey et al., "Measurement of bone collagen degradation in hyperthyroidism and during thyroxine replacement . . . " J. Clin. Endocrin Metab., 72:1189-94 (1991).
Robins et al., "Evaluation of urinary hydroxypridinium crosslink measurements as resorption markers in metabolic bone diseases" Eur. J. Clin. Invest. 21:310-5 (1991).
Seibel et al., "Urinary hydroxypyridinium crosslinks provide indices of cartilage and bone involvement in arthritic diseases" J. Rheumatol., 16:964-70 (1989).
Elomaa et al., "Serum concentration of the cross-linked carboxyterminal telopeptide of type I collagen . . . " Br. J. Cancer 66:337-41 (1992).
Body et al., "Urinary pyridinium cross-links as markers of bone resorption in tumor-associated hypercalcemia" J. Clin. Endocrin Metab., 74:471-5 (1992).
Delmas et al., "Urinary excretion of pyridinoline crosslinks correlates with bone turnover measured on iliac . . . " J. Bone Miner Res. 6:639-44 (1991).
Robins et al., "Measurement of the crosslinking compound, pyridinoline, in urine as an index of collagen degradation in joint disease," Annals of the Rheumatic Diseases, vol. 45, pp. 969-973 (1986).
Kanan Paul G.
Rudnick Ellen
Smith Richard H.
Bio-Quant, Inc.
Hutzell Paula K.
Wolski Susan C.
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