Method of modulating tumor immunity

Details Method of modulating tumor immunity Method of modulating tumor immunity

2005-10-11

2005-10-11

Chan, Christina (Department: 1644)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Animal or plant cell

C424S577000, C435S373000, C435S375000

Reexamination Certificate

active

06953576

ABSTRACT:
Novel cells and molecules involved in tumor immunity are disclosed. The novel cells are regulatory T-cells having the phenotype CD3+αβ-TcR+CD4−CD8−CD44−CD28−NK1.1−. The regulatory cells express Ly6A and osteopontin while non-regulatory cells do not.

REFERENCES:
Chatterjee et al. Cancer Immunol. Imunother., 1994, v.38, pp. 75-82.
Dermer Biotechnology 12: 320, 1994.
Sussman et al.Annals of Surgical Incology, 1994, v.1 p296-306.
Klingemann J. of Hematotheraphy and Stem Cell Research, 2001, v.10, p23-26.

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