Method of modulating tissue growth using Frzb Protein

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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Reexamination Certificate

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06924367

ABSTRACT:
An isolated cDNA encoding a growth-inducing protein, Frzb, capable of stimulating bone, cartilage, muscle, and nerve tissue formation. Frzb binds to and modulates the activity of Wnt growth factors which play a role in various developmental and neoplastic processes. The cDNA and protein sequences of human, bovine andXenopusFrzb are provided. Production and purification of recombinant Frzb are also described.

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