Method of modulating the basal metabolic rate of a dieting...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S177000, C514S182000

Reexamination Certificate

active

10340980

ABSTRACT:
Modulating the metabolism of a dieting mammal by administering to the dieting mammal the metabolic modulating agent 7-oxo DHEA or a pro-drug thereof incapable of in vivo conversion to testosterone.

REFERENCES:
patent: 4666898 (1987-05-01), Coleman et al.
patent: 4920115 (1990-04-01), Nestler et al.
patent: 5296481 (1994-03-01), Partridge et al.
patent: 5424463 (1995-06-01), Lardy et al.
patent: 5506223 (1996-04-01), Lardy et al.
patent: 5807848 (1998-09-01), Lardy
patent: 6399085 (2002-06-01), Zenk et al.
patent: 6465446 (2002-10-01), Dykstra
patent: 873699 (1953-04-01), None
patent: 45-37770 (1966-03-01), None
patent: WO 02/43737 (2002-06-01), None
Wester's II New Riverside University Dictionary, 1984, p. 376.
Yen, Terence, et al. (1977) “Prevention of Obesity inAvy/aMice by Dehydroepiandrosterone”,Lipids, vol. 12, No. 5, (409-413).
Schwartz, Arthur G. et al. (1981) “Dehydroepiandrosterone: An Anti-Obesity and Anti-Carcinogenic Agent”,Nutrition and Cancer An International Journal; vol. 3, No. 1 (46-53).
Cleary, Margot P. et al. (1983) “Effect of Dehydroepiandrosterone on Body Weight and Food Intake in Rats”,Nutrition and Behavior; vol. 1, No. 2 (127-136).
Staber, Lisa D. et al. (1983) “Effects of Dietary Dehydroepiandrosterone on Body Weight and Food Consumption in Lethal Yellow (Ay/Aw) and White-Bellied Agouti (Aw/Aw) Mice (Strain 129/Sv)”,Proceedings of the South Dakota Academy of Science; vol. 62 (154-162).
Weindruch, Richard et al. (1984) “Food Intake Reduction and Immunologic Alterations in Mice Fed Dehydroepiandrosterone”,Experimental Gerontology, vol. 19 (297-304).
Shepherd, Alene et al. (1984) “Metabolic Alterations after Dehydroepiandrosterone Treatment in Zucker Rats”,American Journal of Physiology, vol. 246, No. 2 (123-128).
Coleman, Douglas L. (1985) “Antiobesity Effects of Etiocholanolones in Diabetes (db), Viable Yellow (Avy), and Normal Mice”,Endocrinology, vol. 117, No. 6 (2279-2283).
Cleary, Margot P. et al. (1986) “Anti-Obesity Effect of Two Different Levels of Dehydroepiandrosterone in Lean and Obese Middle-Aged Female Zucker Rats”,International Journal of Obesity10, 193-204.
Tagliaferro, Anthony R. (1986) Effects of Dehyroepiandrosterone Acetate on Metabolism, Body Weight and Composition of Male and Female Rats1,2,The Journal of Nutrition, vol. 116, No. 10 (1977-1983).
Nestler, John E. et al. (1988) Dehydroepiandrosterone Reduces Serum Low Density Lipoprotein Levels and Body Fat but Does not Alter Insulin Sensitivity in Normal Men,The Journal of Clinical Endocrinology&Metabolism, vol. 66, No. 1 (57-61).
Mohan, Pamarthi F. (1988) “Effect of Short-term DHEA Administration on Liver Metabolism of Lean and Obese Rats”,American Journal of Physiology, vol. 255, No. 1 (1-8).
Lardy, Henry et al. (1989) “Dehydroepiandrosterone Induces Enzymes That Permit Thermogenesis and Decrease Metabolic Efficiency”,Hormones, Thermogenesis, and Obesity, Institute for Enzyme Research, University of Wisconsin-Madison, Madison, Wisconsin, USA. (415-426).
Nestler, John E. et al. (1989) Dehydroepiandrosterone: Effects on Insulin Sensitivity, Serum Lipid Levels, and Body Composition in Normal Men,Hormones, Thermogenesis, and Obesity, Division of Endocrinology and Metabolism, Medical College of Virginia/Virginia Commonwealth University; Richmond, Virginia, USA (405-414).
Schauer, Jane E. (1989) “Effects of Acute and Chronic Exercise in Rats on Energy Transduction under the Influence of Dehydroepiandrosterone and β-Agonist”,Hormones, Thermogenesis, and Obesity, Institute for Enzyme Research, Madison, Wisconsin, USA., Uniformed Services University of Health Sciences, F. Edward Herbert School of Medicine, Bethesda, Maryland, USA. (485-501).
Cleary, M. P. (1989) Antiobesity Effect of Dehydroepiandrosterone in the Zucker Rat,Hormones, Thermogenesis, and Obesity, The Hormel Institute, University of Minnesota, Austin, Minnesota, USA (365-376).
MacEwen, E. Gregory (1989) “Antiobesity and Hypocholesterolemic Activity of Dehydroepiandrosterone (DHEA) in the Dog”,Hormones, Thermogenesis, and Obesity, Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA (399-404).
Su, Ching-Yuan (1988) Induction of Hepatic Mitochondrial Glycerophosphate Dehydrogenase and Malic Enzyme 1. Effects of Dehydroepiandrosterone 2. Effects of Dehydroepiandrosterone-Related Steroids and Cytochrome P-450 Inducers, University of Wisconsin-Madison (1-126).
Lardy, Henry et al., (1990), “Biochemical Aspects of Obesity”, Annual Revue.
Usiskin, Keith S. et al. (1990) “Lack of Effect of Dehydroepiandrosterone in Obese Men”,International Journal of Obesity, vol. 14, No. 5 (457-463).
Mortola, J. F. et al. (1990) “The Effects of Oral Dehydroepiandrosterone on Endocrine-Metabolic Parameters in Postmenopausal Women”,Clinical Endocrinology&Metabolism, vol. 71, No. 3 (696-704).
Mohan, Pamarthi F. et al. (1990) Effects of Dehydroepiandrosterone Treatment in Rats with Diet-Induced Obesity1,2,The Journal of Nutrition, vol. 120, No. 9 (1103-1114).
Welle, Stephen et al. (1990) “Failure of Dehydroepiandrosterone to Influence Energy and Protein Metabolism in Humans”, The Journal of Clinical Endocrinology & Metabolism, vol. 71, No. 5 (1259-1264).
Nestler, John E. et al. (1991) “Metabolism and Actions of Dehydroepiandrosterone in Humans”,The Journal of Steroid Biochemistry and Molecular Biologyvol. 40, No. 4-6 (599-605).
Su, Ching-Yuan et al. (1991) Induction of Hepatic Mitochondrial Glycerophosphate Dehydrogenase in Rats by Dehydroepiandrosterone1,J. Biochem., 110 (207-213).
Bobyleva, Valentina et al. (1993) “Concerning the Mechanism of Increased Thermogenesis in Rats Treated with Dehydroepiandrosterone”,Journal of Bioenergetics and Biomembranes, vol. 25, No. 3 (313-321).
Morales, Arlene J. et al. (1994) Effects of Replacement Dose of Dehydroepiandrosterone in Men and Women of Advancing Age,Journal of Clinical Endocrinology and Metabolism, vol. 78, No. 6 (1360-1367).
Regelson, William et al. (1994) “Dehydroepiandrosterone (DHEA)—the Multifunctional Steroid”,The Aging Clock The Pineal Gland and Other Pacemakers in the Progression of Aging and Carcinogenesis, vol. 719 (564-575).
Lardy, Henry et al. (1995) “Ergosteroids: Induction of Thermogenic Enzymes in Liver of Rats Treated with Steroids Derived from Dehydroepiandrosterone”,Proc. Natl. Acad. Sci. USA, vol. 92 (6617-6619).
[Author unkown] (1995) “Guidelines for the Approval and Use of Drugs to Treat Obesity”,Obesity Research, vol. 3, No. 5 (473-478).
Shealy, C. Norman (1995) “A Review of Dehydroepiandrosterone (DHEA)”,Integrative Physiological and Behavioral Science, vol. 30, No. 4 (308-313).
Casson, Peter R. et al. (1995) “DHEA Administration to Humans: Panacea or Palaver?”,Seminars in Reproductive Endocrinology, vol. 13, No. 4 (247-256).
Kurzman, Ilene D., (1998), The Effect of Dehydroepiandrosterone combined with a Low-Fat Diet in Spontaneously Obese Dogs: A Clinical Trial, Obesity Research, vol. 6 No. 1.
AdvantRx Corporation (2000), “Eating and Exercise Plan”.
Active Nutraceuticals (2002), “. . . experience the miracle”.
Humanetics Corporation (2002), “7 Keto The #1 Selling Non-Stimulant Weight Loss Ingredient”.
Zenk, John L. M.D. (1999), “Humanetics Health Facts”,7 Keto.
Humanetics Corporation (2001), www.humaneticscorp.com/.
Humanetics Corporation, “Push Down and Turn-Up The Safety and Potency of DHEA”.
Humanetics Corporation (1998), “Squeeze Sides and Lift-Up the Benefits of DHEA Without the Worry”.
The Effects of the Ergosteroid 7-Oxo-dehydroepiandrosterone on Mitochondrial Membrane Potential: Possible Relationship to Thermogenesis, Bobyleva et al., Archive of Biochemistry and Biophysics, vol. 342

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of modulating the basal metabolic rate of a dieting... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of modulating the basal metabolic rate of a dieting..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of modulating the basal metabolic rate of a dieting... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3760827

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.