Method of microencapsulation

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

Reexamination Certificate

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C264S004330, C264S004600, C427S212000, C427S213300, C427S213360, C428S402200, C428S402210, C428S402220, C428S402240, C523S105000, C424S493000, C424S494000, C424S495000, C424S497000, C424S501000

Reexamination Certificate

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06932984

ABSTRACT:
A method for microencapsulation of substances is provided. The substance(s) is/are dissolved or dispersed in an organic solvent of the kind that is partially miscible in water media. This organic solution is then mixed with an aqueous solution, which is saturated with an organic solvent and an emulsifier to form an emulsion. The emulsion is then poured into water under continuous agitation for the extraction of residual solvent. The formation of the solid capsules takes place during this extraction process. The capsules are undergone to further purification, whereby the microcapsules can be separated from the water and dried. By conditions of incubation of microcapsules in water-containing formulations the wall-softening process takes place. The unique system for controlled releasing the ingredients from microcapsules is based on the above-mentioned process.

REFERENCES:
patent: 3737337 (1973-06-01), Schnoring et al.
patent: 3891570 (1975-06-01), Fukushima et al.
patent: 3951851 (1976-04-01), Kitajima et al.
patent: 4384975 (1983-05-01), Fong
patent: 5916598 (1999-06-01), Pickey et al.
patent: 2 766 368 (1999-01-01), None

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