Method of medical treatment of Alzheimer's disease

Details Method of medical treatment of Alzheimer's disease Method of medical treatment of Alzheimer's disease

1988-12-06

1990-08-21

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

A61K 3166

Patent

active

049506587

ABSTRACT:
This invention relates to a method for improving memory and accompanying symptoms in patients with Alzheimer's disease and related disorders of memory. The method includes the steps of dosing a patient with 2,2-dichlorovinyl dimethyl phosphate sometimes referred to as dichlorvos or DDVP, or a precursor thereof maintaining said dosage at a level and over a period of time sufficient to create a concentration of DDVP in the brain whereby memory improvement occurs. A satisfactory precursor for this method is 2,2,2-trichloro-1-hydroxyethyl dimethyl phosphate sometimes referred to as metrifonate and 1,2-dibromo, 2-dichlorvoethyl dimethyl phosphate sometimes referred to as naled. Other precursors are also useful.

REFERENCES:
patent: 2701225 (1955-02-01), Lorenz
patent: 3067096 (1962-12-01), Trace et al.
patent: 3111457 (1963-11-01), Trace et al.
patent: 3233513 (1965-12-01), Geary
patent: 3264175 (1966-08-01), Heim
patent: 3801710 (1974-04-01), Parish et al.
patent: 4141975 (1979-02-01), Gay et al.
patent: 4277467 (1981-07-01), Dorn et al.
patent: 4288451 (1981-09-01), Mues et al.
American Society of Hospital Pharmacists "American Hospital Formulary Service" p. 1376.
Copy of Computer Search Conducted in Dialog 2, Files 23,24,25,26,229,300,301,328,320,330,331,399,308,309,320,310 and 311.

Affiliated with

Also associated with

Rating

Method of medical treatment of Alzheimer's disease does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of medical treatment of Alzheimer's disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of medical treatment of Alzheimer's disease will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1677810