Method of measuring the efficiency of mass and energy transfer i

Surgery – Blood drawn and replaced or treated and returned to body

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210646, B01D 1100

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active

061560022

ABSTRACT:
A method for measurement of mass and energy transfer parameters (clearance and dialysance) in hemodialysis. A sensor is provided in the dialysate flow path downstream of the dialyzer and means are provided to add concentrate upstream of the dialyzer. A pre-determined amount of a substance whose dialysance is to be measured is added upstream of the dialyzer. The amount of substance not dialyzed in the dialyzer is measured downstream of the dialyzer by said sensor by integrating the concentration over time. Dialysance is calculated from the amount added upstream, the amount measured downstream and the dialysate flow. In case the substance is part of the dialysate the base concentration is subtracted during integration. The addition of the concentrate upstream of the dialyzer can be done manually or, alternatively by the mixing pump of the dialysis machine. Instead of an increase of the concentration with a concentrate dilution with water can be used as well.

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patent: 5744027 (1998-04-01), Connell et al.
patent: 5744031 (1998-04-01), Bene
patent: 5928180 (1999-07-01), Krivitiski et al.

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