Method of measuring PTX3 with high sensitivity

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S070210, C435S810000, C530S387100, C530S388100, C530S388240

Reexamination Certificate

active

07955807

ABSTRACT:
To provide a method of determining vasculopathy, which is a risk factor of myocardial infarction, angiopathic dementia, etc., at an early stage thereof (i.e., mild vasculopathy). The present invention provides a method of determining the severity of mild vasculopathy, including determining PTX3 level in an assay sample by use of an anti-PTX3 monoclonal antibody.

REFERENCES:
patent: 2004/0137544 (2004-07-01), Latini et al.
patent: 2008/0261251 (2008-10-01), Mantovani et al.
patent: 7 209293 (1995-08-01), None
patent: 11 1494 (1999-01-01), None
patent: 2000 297098 (2000-10-01), None
patent: 01 25427 (2001-04-01), None
patent: 2005 080981 (2005-09-01), None
U.S. Appl. No. 10/590,526, filed Aug. 24, 2006, Kodama, et al.
Mariam Klouche, et al., “Modified Atherogenic Lipoproteins Induce Expression of Pentraxin-3 by Human Vascular Smooth Muscle Cells”,Atherosclerosis, XP002508603, vol. 175, No. 2, Aug. 2004, pp. 221-228.
Ferruccio Breviario, et al., “Interleukin-1-Inducible Genes in Endothelial Cells”, Cloning of a New Gene Related to C-Reactive Protein and Serum Amyloid P Component, The Journal of Biological Chemistry, vol. 267, No. 31, Issue of Nov. 5, pp. 22190-22197, 1992.
Michael S. Rolph, et al., “Atherosclerosis and Lipoproteins” “Rapid Communication Production of the Long Pentraxin PTX3 in Advanced Atheosclerotic Plaques”, Arterioscler Thromb Vasc Biol., 22 (5) : e10-14, May 1, 2002.
Kaoru Hatanaka, et al., “Molecular Biology of Acute Phase Proteins Pentaxin Family”, Arterial Sclerosis 24(7.8): pp. 375-380, 1996.
Fausto Fazzini, et al., “PTX3 in Small-Vessel Vasculitides”, An Independent Indicator of Disease Activity Produced at Sites of Inflammation, Arthritis & Rheumatism, vol. 44, No. 12, Dec. 2001, pp. 2841-2850.
Giuseppe Peri, et al., “PTX3, a Prototypical Long Pentraxin, is an Early Indicator of Acute Myocardial Infarction in Humans”, Downloaded from circ.ahajournals.org by on May 30, 2008.

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