Method of measuring dipeptidyl-amino-peptidase activity

Details Method of measuring dipeptidyl-amino-peptidase activity Method of measuring dipeptidyl-amino-peptidase activity

1978-04-17

1980-03-04

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

G01N 3114

Patent

active

041918088

ABSTRACT:
The activity of X-prolyl dipeptidyl-aminopeptidase against X-L-proline-Y wherein X is an amino acid residue and Y is p-nitroaniline, p-phenylazoaniline or 4-phenylazo-1-naphthylamine is used as a measure of human afflictions such as hepatobiliary diseases and carcinomas.

REFERENCES:
patent: 4016042 (1977-04-01), Svendsen
patent: 4061625 (1977-12-01), Ekenstum et al.
patent: 4070245 (1978-01-01), Svendsen
Hino, et al., "Glycyclprolyl .beta.-Naphthylamidase Activity in Human Serum", Clin. Chim. Acta., vol. 62 (1975), pp. 5-11.
Pettit, Synthetic Peptides I, (1971), pp. 124-125.

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