Method of measuring collagenase activity

Details Method of measuring collagenase activity Method of measuring collagenase activity

1977-11-21

1979-11-27

Jones, Raymond N.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

G01N 3114

Patent

active

041760093

ABSTRACT:
A method of measuring collagenase activity using as substrates peptide derivatives having the structure A-Pro-B-Gly-C-Ala-Gly-E wherein A is a hydrophobic neutral or acidic chromophore, B is an amino acid residue, C is Ile or Leu, E is Gln-D-Arg-OH or D-Arg-OH and all the amino acid residues except for Gly are L-configuration unless otherwise stated.

REFERENCES:
patent: 4016042 (1977-04-01), Svendsen
patent: 4028318 (1977-06-01), Aurell et al.
patent: 4070245 (1978-01-01), Svendsen
patent: 4119620 (1978-10-01), Nagatsu et al.
Appel, "Collagenases", Methods of Enzymatic Analysis, Bergmeyer (Ed.), (1974), vol. 2, Academic Press, Inc., New York, pp. 1058-1063.

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