Method of measuring a catecholamine and its metabolite

Details Method of measuring a catecholamine and its metabolite Method of measuring a catecholamine and its metabolite

1993-10-06

1995-01-03

Housel, James C.

Chemistry: analytical and immunological testing

Nitrogen containing

Amine and quaternary ammonium

436172, 436175, 436800, 436813, G01N 2165, G01N 3374

Patent

active

053786351

ABSTRACT:
A method of measuring at least one of a catecholamine and its metabolite including a biological sample pretreatment process, a fluorescence inducing process of converting into a fluorescence inductor the at least one of a catecholamine and its metabolite in the biological sample subjected to pretreatment by means of a fluorescence inducing reagent, and a measuring process of separating and measuring said fluorescence inductor by liquid chromatography, said method being characterized by addition of a specified volume of maleimide before said process of making the biological sample fluorescent.

REFERENCES:
patent: 4680272 (1987-07-01), Smith
F. A. J. Van der Hoorn et al., Journal of Chromatography, 487, pp. 17-28 (1989).

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