Radiant energy – Ionic separation or analysis – Methods
Reexamination Certificate
2006-09-26
2006-09-26
Lee, John R. (Department: 2881)
Radiant energy
Ionic separation or analysis
Methods
C250S281000, C250S287000, C250S288000, C250S290000
Reexamination Certificate
active
07112784
ABSTRACT:
A method of mass spectrometry is disclosed wherein a gas collision cell is repeatedly switched between a fragmentation and a non-fragmentation mode. Parent ions from a first sample are passed through the collision cell and parent ion mass spectra and fragmentation ion mass spectra are obtained. Parent ions from a second sample are then passed through the collision cell and a second set of parent ion mass spectra and fragmentation ion mass spectra are obtained. The mass spectra are then compared and if either certain parent ions or certain fragmentation ions in the two samples are expressed differently then further analysis is performed to seek to identify the ions which are expressed differently in the two different samples.
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Bateman Robert Harold
Langridge James Ian
McKenna Therese
Richardson Keith
Diederiks & Whitelaw PLC
Lee John R.
Micromass UK Limited
Vanore David A.
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