Method of manufacturing lactulose

Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge

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2041826, 127 30, 127 40, 127 462, 127 54, 536125, C07H 304, C07C 4718

Patent

active

050715305

ABSTRACT:
For the manufacture of lactulose, an alkaline aqueous solution of lactose and borax is prepared and heated at a temperature above 80.degree. C. The lactulose is separated from the resulting conversion products. Apart from the borax, no alkalizing material is added to the solution. The conversion is carried out at pH 8.3.
In order to maintain the sodium ions in the production cycle, the borax may be manufactured in an aqueous solution of boric acid and already simultaneously with the lactose, while the sodium ions are transferred from the solution of the conversion products in the solution of the boric acid by electrodialysis.
Alternatively the sodium ions may also be removed from the solution of the conversion products as readily as possible by means of a weakly acid ion exchanger and only thereafter by means of a more strongly acid ion exchanger.
The weakly acid ion exchanger is regenerated with boric acid so that borax is formed again.

REFERENCES:
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patent: 3715235 (1973-02-01), Moebes et al.
patent: 3850905 (1974-11-01), Tumerman
patent: 4226977 (1980-10-01), Neuzil et al.
patent: 4264763 (1981-04-01), Gasparotti
patent: 4273922 (1981-06-01), Hicks
patent: 4394178 (1983-07-01), Chao et al.
patent: 4536221 (1985-08-01), Carobbi et al.
patent: 4555271 (1985-11-01), Carobbi et al.
patent: 4565582 (1986-01-01), Filippini et al.

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