Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-10-07
1981-10-27
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602395, A61K 3158
Patent
active
042973511
ABSTRACT:
New and pharmacologically useful pharmaceutically acceptable acid addition salts are disclosed for the 16.beta.-monoquaternary ammonium derivatives of either the 2.beta., 16.beta.-bis-piperdino-3.alpha., 17.beta.-dihydroxy-5.alpha.-androstane 3.alpha., 17.beta.-di-lower aliphatic esters or the 2.beta., 16.beta.-bis-piperidino-3.alpha.-hydroxy-5.alpha.-androstane-3.alpha.-lowe r aliphatic esters, which salts are surprisingly relatively stable in aqueous solutions, so that they provide stable aqueous injection preparations.
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patent: 4101545 (1978-07-01), Tuba et al.
patent: 4110326 (1978-08-01), Tuba et al.
patent: 4177190 (1979-12-01), Tuba et al.
W. R. Buckett et al., Pancuronium Bromide and Other Steroidal Neuromuscular Blocking Agents Containing Acetylcholine Fragments, J. Medicinal Chem. 16(10), at pp. 1116 to 1123 (1073).
Carlyle Ian C.
Savage David S.
Sleigh Thomas
Akzona Incorporated
Falk Robert H.
Roberts Elbert L.
Wendel Charles A.
Young Francis W.
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