Method of making staphylococcus aureus vaccine

Details Method of making staphylococcus aureus vaccine Method of making staphylococcus aureus vaccine

1989-04-04

1991-07-16

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435883, 424 92, C12N 0120, A61K 3902

Patent

active

050325221

ABSTRACT:
The present invention provides an in vitro method of culturing Staphylococcus aureus to produce anti-phagocytic pseudocapsular antigens which heretofore were only produced by in vivo culturing techniques. The invention also provides a method for making a killed Stophylococcus aureus vaccine containing the anti-phagocytic pseudocapsular antigen produced in an in vitro culturing method. The anti-phagocytic pseudocapsular antigens are produced by culturing Staphylococcus aureus in a nutrient medium containing milk, milk whey and like milk products. The killed bacteria is useful for treating mastitis caused by Staphylococcus aureus.

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