Method of making pharmaceutical using electrostatic chuck

Details Method of making pharmaceutical using electrostatic chuck Method of making pharmaceutical using electrostatic chuck

1996-04-09

1998-12-08

Beck, Shrive

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Particulate or unit-dosage-article base

427 231, 427 8, 427466, 427475, 427483, B05D 104, B05D 106, A61J 302

Patent

active

058465952

ABSTRACT:
The present invention is directed to electrostatic chucks, methods for their use, the electrostatic deposition of particles on an objects, and the objects themselves that have been subjected to electrostatic deposition. In one aspect, the present invention provides an electrostatic chuck for electrostatically attracting an object or objects wherein the object is used in chemical or pharmaceutical assaying or manufacturing, and optionally wherein the object is less than or equal to one millimeter in average width or diameter. The objects can be pharmaceutical substrates, for example, such as a pharmaceutical tablet. Additional embodiments of the invention provide chucks and their use to electrostatically attract particles, such as a pharmaceutically active ingredient, to a substrate, such as a tablet. In one aspect, the electrostatic chuck comprises a floating electrode, and is used to selectively attract particles to a substrate above the floating electrode, thereby providing for charge imaging for the deposition of particles in a selected image. Additionally, the invention provides an electrostatic chuck comprising a sensing electrode for sensing the number of particles attracted to the chuck, thereby providing for deposition of an accurate amount of particles. Furthermore, the present invention provides objects having selected areas in which particles are applied to the object via electrostatic means.

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