Method of making oligonucleotide libraries

Details Method of making oligonucleotide libraries Method of making oligonucleotide libraries

1994-01-11

1996-12-24

Guzo, David

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 254, 536 2541, C07H 2100

Patent

active

055874711

ABSTRACT:
The present invention provides methods of analyzing and evaluating phosphorus bearing monomeric units as to their suitability for use in preparing randomer oligomer libraries. The invention further provides methods for preparing such randomer oligomer libraries from the selected monomers.

REFERENCES:
patent: 3687808 (1972-08-01), Merigan et al.
Anderson et al., "Synthesis of Pyrazolo[3,4-d] Pyrimidine Ribonucleoside 3', 5'-Cyclic Phosphates Related to cAMP, cIMP and cGMP", Nucleosides and Nucleotides 6: 853-863 (1987).
Nord et al., "Synthesis, Structure, and Biological Activity of Certain 2-Deoxy-.beta.-D-ribo-hexopyranosyl Nucleosides and Nucleotides", J. Med. Chem 30: 1044-1054 (1987).
Ugarkar et al., "A Simple Oxidation of Formycin to Oxoformycin and Oxoformycin B. Syntehsis of 6-Methyloxoformycin, a C-Nucleoside Analog of Doridosine" J. Heterocyclic Chem 21: 1865-1870 (1984).

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