Method of making modified-release metronidazole compositions

Details Method of making modified-release metronidazole compositions Method of making modified-release metronidazole compositions

1995-05-19

1997-04-08

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424487, 424501, 427 215, 427213, A61K 922, A61K 916, A61K 4732

Patent

active

056185596

ABSTRACT:
Pharmaceutical compositions having a modified release profile for once daily dosing of metronidazole, methods for making the pharmaceutical compositions, and methods for treating a microbial infection with once daily dosing of the pharmaceutical compositions of the invention are provided. The compositions given once daily exhibit substantial bioequivalence to immediate release metronidazole given three times per day. The compositions of the invention comprise:

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