Method of making metallopeptides

Details Method of making metallopeptides Method of making metallopeptides

2005-09-07

2008-09-16

Wessendorf, T. D. (Department: 1639)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Synthesis of peptides

C530S335000, C530S334000, C530S333000, C530S326000, C530S327000, C530S328000, C530S329000, C530S330000, C530S331000

Reexamination Certificate

active

07425608

ABSTRACT:
Method of making metallopeptides is provided, for use in biological, pharmaceutical and related applications. The metallopeptides are made of peptides, peptidomimetics and peptide-like constructs, and include a metal ion-binding region thereof which includes at least one orthogonal sulfur-protecting group, in which the peptide, peptidomimetic or construct is conformationally fixed on deprotection of the sulfur and complexation of the metal ion-binding region with a metal ion while the peptide, peptidomimetic or construct is cleavably bound to solid phase.

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