Method of making liquid chromatography packing materials

Catalyst – solid sorbent – or support therefor: product or process – Solid sorbent – Organic

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502158, 502407, B01J 2022, B01J 2010

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049593404

ABSTRACT:
Packing materials for use in liquid chromatographic analysis are prepared by contacting a porous support, such as porous silica, with a ketal silane to form ketal blocked diol groups on the surfaces thereof. An end-capping reagent such as a trimethylsilyl reagent may be added. In addition, the ketal blocked diol groups may be further hydrolyzed to diol groups.

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