Method of making intraocular lenses with injectable collagen-bas

Details Method of making intraocular lenses with injectable collagen-bas Method of making intraocular lenses with injectable collagen-bas

1993-11-24

1995-12-19

Prebilic, Paul B.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Eye prosthesis

Intraocular lens

623 4, 623901, 606107, 424424, 424427, A61F 216

Patent

active

054765153

ABSTRACT:
Injectable collagen-based compositions can be used in methods to fill a lens capsular sac, following lens extraction procedures, to form a new intraocular lens. Purified soluble or partially fibrillar collagen may be modified with acylating agents, sulfonating agents or combinations thereof to form a clear, transparent collagen composition having indices of refraction between about 1.2 to 1.6. The modified collagen may injected into a lens capsular sac to form an intraocular lens (IOL) in situ. The IOL is clear, transparent, resistant to epithelialization and is capable of accommodation. The collagen-based IOL produced by the method of the present invention may remain in its original viscous liquid state or may be polymerized into a soft gel. The collagen-based IOL may be used to replace diseased or natural lens to treat cataracts, presbyopia, myopia and hyperopia.

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