Method of making inosine monophosphate derivatives and immunopot

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536 278, 536 267, C07H 1920, A61K 3170

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056145047

ABSTRACT:
A method of making inosine-5'-monophosphate and its derivatives resistant to 5'-nucleotidase by chemically modifying inosine-5'-monophosphate to the formula: ##STR1## wherein R is selected from the group consisting of an alkyl, alkoxy and secondary amino compounds whereby inosine-5'-monophosphate biological activity is retained in vitro and extended to in vivo.

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