Method of making halobenzophenones and intermediates thereof

Details Method of making halobenzophenones and intermediates thereof Method of making halobenzophenones and intermediates thereof

1989-11-13

1990-12-18

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

570144, 570184, 568323, C07C 4565

Patent

active

049787985

ABSTRACT:
Disclosed is a method of making a bisphenyl dihalomethane by reacting a trihalomethylbenzene with a halobenzene and a Lewis acid. The bisphenyl dihalomethane can than be reacted with water to form a halobenzophenone. In an optical third step ring chlorines that are present can be replaced with fluorines and, in a final step, any remaining chlorines can be removed to leave a fluorobenzophenone. The process is particularly useful in making 4,4'-difluorobenzophenone, which is in turn useful in making polyetheretherketones.

REFERENCES:
patent: 3017440 (1962-01-01), Entemann
patent: 4263458 (1981-04-01), Bowden
patent: 4320224 (1982-03-01), Rose et al.
patent: 4453009 (1984-06-01), Vamaguchi et al.
patent: 4453012 (1984-06-01), Desbois
Feiser et al., "Reagents for Organic Synthesis", p. 1026, (1967).

Affiliated with

Also associated with

Rating

Method of making halobenzophenones and intermediates thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of making halobenzophenones and intermediates thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of making halobenzophenones and intermediates thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1426600