Coating processes – Direct application of electrical – magnetic – wave – or... – Electromagnetic or particulate radiation utilized
Reexamination Certificate
2007-09-21
2009-08-25
Kornakov, Michael (Department: 1792)
Coating processes
Direct application of electrical, magnetic, wave, or...
Electromagnetic or particulate radiation utilized
C073S023200, C073S024010, C073S024060, C073S064530, C427S299000, C427S327000, C427S337000
Reexamination Certificate
active
07579052
ABSTRACT:
Highly sensitive sensor platforms for the detection of specific reagents, such as chromate, gasoline and biological species, using microcantilevers and other microelectromechanical systems (MEMS) whose surfaces have been modified with photochemically attached organic monolayers, such as self-assembled monolayers (SAM), or gold-thiol surface linkage are taught. The microcantilever sensors use photochemical hydrosilylation to modify silicon surfaces and gold-thiol chemistry to modify metallic surfaces thereby enabling individual microcantilevers in multicantilever array chips to be modified separately. Terminal vinyl substituted hydrocarbons with a variety of molecular recognition sites can be attached to the surface of silicon via the photochemical hydrosilylation process. By focusing the activating UV light sequentially on selected silicon or silicon nitride hydrogen terminated surfaces and soaking or spotting selected metallic surfaces with organic thiols, sulfides, or disulfides, the microcantilevers are functionalized. The device and photochemical method are intended to be integrated into systems for detecting specific agents including chromate groundwater contamination, gasoline, and biological species.
REFERENCES:
patent: 5270163 (1993-12-01), Gold et al.
patent: 5485096 (1996-01-01), Aksu
patent: 6575020 (2003-06-01), DeCharmoy Grey et al.
patent: 6617040 (2003-09-01), Houser et al.
patent: 2003/0010097 (2003-01-01), Porter et al.
patent: 2003/0222232 (2003-12-01), Welland et al.
patent: 2004/0152211 (2004-08-01), Majumdar et al.
patent: 02003166990 (2003-06-01), None
patent: WO02/19407 (2002-07-01), None
patent: 03/044530 (2003-05-01), None
patent: 03/062135 (2003-07-01), None
patent: 03/067248 (2003-08-01), None
patent: 03/071258 (2003-08-01), None
patent: 03/104784 (2003-12-01), None
patent: 2004/059306 (2004-07-01), None
patent: 2007011376 (2007-01-01), None
Pinnaduwage, L.A. et al.“Sensitive Detection of Plastic Explosives with Self-Assembled Monolayer-Coated Microcantilevers.” Applied Physics Letters, vol. 83, No. 7 (Aug. 18, 2003), pp. 1471-1473.
Turyan, Iva et al.“Selective Determination of Cr(VI) by a Self-Assembled Monolayer-Based Electrode.” Anal. Chem., vol. 69 (1997), pp. 894-897.
Hai-Feng, Ji et al.“Ultrasensitive Detection of CrO4 2- Using a Microcantilever Sensor.” Anal. Chem., vol. 73 (2001), pp. 1572-1576.
European Patent Office, PCT/US2005/032877, “International Search Report,” Feb. 1, 2007.
Andreas Hierlemann and Henry Baltes, “CMOS-Based Chemical Microsensors,” The Royal Society of Chemistry Journal, 2003, pp. 15-28, vol. 128.
Min Yue, et al., “A 2-D Microcantilever Array for Multiplexed Biomolecular Analysis,” Jornal of Microelectromechanical Systems, 2004, pp. 290-299, vol. 13, No. 2.
M. Alvarez, et al., “Nanomechanics for Specific Biological Detection,” Proceedings of SPIE, 2003, pp. 197-206, vol. 5118.
Iva Turyan and Daniel Mandler, “Selective Determination of CR(VI) by a Self-Assembled Monolayer-Based Electrode,” Anal. Chem., 1997, pp. 894-897, vol. 69.
F. Tian, et al., “Selective Detection of CR(VI) Using a Microcantilever Electrode Coated with a Self-Assembled Monolayer,” J. Vac. Sci, Technol. A, 2005, pp. 1022-1028, vol. 23, No. 4.
Robert L. Gunter, et al., Investigation of DNA Sensing Using Piezoresistive Microcantilever Probes, IEEE Sensors Journal, 2004, pp. 430-433, vol. 4, No. 4.
J. Terry, et al., “Determination of the Bonding of Alkyl Monolayers to the Si(111) Surface Using Chemical-Shift . . . ,” Appl Phys Lett, 1997, pp. 1056-1058, vol. 71, Issue 8.
J. Terry, et al., “Reactivity of the H-Si (111) Surface,” Nucl Instrum Methods Phys Res, Sect B, 1997, pp. 94, vol. 133.
J. Terry, et al., “Alkyl-Terminated Si(111) Surfaces: A High-Resolution, Core Level Photoelectron Spectroscopy Study,” J of Appl Phys, 1999, pp. 213-221, vol. 85, No. 1.
R.L. Cicero, et al., Photoreactivity of Unsaturated Compounds with Hydrogen-Terminated Silicon(111), Langmuir, 2000, pp. 5688-5695, vol. 16.
L.A. Pinnaduwage, et al., “Detection of Hexavalent Chromium in Ground Water Using a Single Microcantilever Sensor,” Sensor Letters, pp. 1-6, vol. 2, Issue 1-6.
V.I. Boiadjieve, et al., “Photochemical Hydrosilylation,” Langmuir, 2005.
X. Zhou, et al., “Roles of Charge Polarization and Steric Hindrance in Determining the Chemical Reactivity of Surface Si-H . . . ,” J Phys Chem B, 2001, pp. 156-163, vol. 105.
A. Arafat, et al., “Tailor-Made Functionalization of Silicon Nitride Surfaces,” J Am Chem Soc, 2004, pp. 860-8601, vol. 126.
R. Voicu, et al., “Formation, Characterization, and Chemistry of Undecanoic Acid-Terminated Silicon Surfaces . . . ,” Langmuir, 2004, pp. 11713-11720, vol. 20.
C.M. Yam, et al., “Protein-Resistant Monolayers Prepared by Hydrosilylation . . . ,” Chemical Communications, 2004, pp. 2510-2511.
J. M. Buriak, “Organometallic chemistry on Silicon and Germanium Surfaces,” Chemical Reviews, 2002, pp. 1271-1308, vol. 102, No. 5.
I. Fleming, Comprehensive Organic Chemistry, pp. 568, vol. 3.
Mosier-Boss and Lieberman, “Surface-Enhanced Raman Spectroscopy (SERS) and Molecular Modeling of the Chromate Interaction with . . .” Langmuir, 2003, pp. 6826-6836, vol. 19.
Hai-Feng, et al., “Ultrasensitive Detection of CrO42- Using a Microcantilever,” 2001, Anal. Chem. pp. 1572-1576, vol. 73.
L.A. Pinnaduwage, et al., Sensitive Detection of Plastic Explosives with Self-Assembled Monolayer-Coated Microcantilevers, 2003, Applied Physical Letters, pp. 1471-1473, vol. 83, No. 7.
Boiadjiev Vassil I.
Bonnesen Peter V.
Brown Gilbert M.
Goretzki Gudrun
Pinnaduwage Lal A.
Boyle Fredrickson , S.C.
Kornakov Michael
UT-Battelle LLC
Weddle Alexander
LandOfFree
Method of making gold thiolate and photochemically... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of making gold thiolate and photochemically..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of making gold thiolate and photochemically... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4102245