Method of making glycoprotein exhibiting erythropoiesis...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S325000

Reexamination Certificate

active

06867020

ABSTRACT:
The Apa I restriction fragment of the human erythropoietin gene, for producing high titers of biologically active hormone from stably transfected cell lines.

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patent: WO 8502610 (1985-06-01), None
Nimtz et al, Eur. J. Biochem. 213: 39 (1993).*
Yanagi et al, DNA 8 (6), 419 (1989).*
Lee-Huang et al. “The Human Erythropoietin-Encoding Gene Contains a CAAT Box, TATA Boxes and Other Transcriptional Regulatory Elements in its 5' Flanking Region”, Gene, vol. 128, No. 2, 227-236 (1993).
Maniatis et al., “Molecular Cloning: A laboratory Manual”, 1982.
Berger “Methods in Enzymology”, Guide to Molecular Cloning Techniques, vol. 152, 696-697, 1987.
New England Biolabs Catalog, 1995 p. 14.

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