Method of making cosmetic, pharmaceutical, and...

Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from roseaceae

Reexamination Certificate

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C424S725000, C424S735000, C424S736000, C424S758000, C424S760000, C424S777000, C424S401000, C099S495000, C099S510000, C426S599000, C426S518000, C426S416000

Reexamination Certificate

active

06780444

ABSTRACT:

The present invention relates to in particular cosmetic and/or pharmaceutical and/or dermatological compositions intended in particular to promote the care of the skin. It also relates to the method of manufacture of such compositions.
At all times, one has sought to improve the aspect of the skin and in particular to delay or to eliminate the signs of its ageing. This ageing is reflected among others in the appearance of wrinkles and a loss of firmness of the skin due to a natural slowing down of the renewal of the living cells constituting this skin. The generally proposed solution is to eliminate the dead cells building up at the surface of the skin while promoting its cellular renewal.
The proposed cosmetic compositions are however most often based upon synthetic hence non-natural chemical products of which in addition the manufacture is complex and costly. The treatment of the skin however is not of aesthetic character only.
Thus acne and the lesions it causes originate from sebaceous glands associated with the pilose follicles in particular on the face, the back, the chest. These glands contain cells which secrete a mixture in particular containing triglycerides, fatty acids called “sebum”. In acne, the sebum secretions are increasing, the ducts of the sebaceous glands are thickening and produce black points or comedos and inflammations appear about the sebaceous glands.
The main treatments known for acne either are not really effective (various gels and ointments) or exhibit serious inconveniences whether they are antibiotics (absorption of antibiotics for a long duration through oral or local route, the latter mode risking to create bacteria resistant to the antibiotics), or the retinoids (compounds closely related to the vitamin A which are administered in a hospital environment only and have incidences on the lever).
The eczema is as to it an inflammatory state of the skin characterized by groups of vesicular lesions of variable sizes. The known treatments are generally based upon steroids and/or antibiotics which are medicines which have sometimes serious inconveniences.
Psoriasis and parapsoriasis are pathological pictures which appear on any portion whatsoever of the surface of the body and which even may cover it entirely. The seriousness of the lesions depends on both the extension and the depth at which the psoriasic process affects the dermic layers. An important point of the pathology of psoriasis is that the regeneration of the epidermis is much quicker in the case of psoriasis than for a normal skin (3-4 days instead of 27 days).
Although the disease is known for a long time, the known therapeutics (ultraviolets, tars, dithranol—which should not be put in contact with the healthy skin—, steroids) are very little efficient and/or very penalizing for the patients.
In a both cosmetic and pharmaceutical field, the acids of fruits (alpha-hydroxy acids) which belong to a group of substances extracted from natural products such as citric acid (extracted from fruits), malic acid (extracted from the apple), lactic acid (extracted from milk) assume an increasing importance.
Thus they would be efficient in the treatment of various diseases of the skin, among which acne, in the fight against ageing due to the sun (heliodermy) and for the rejuvenation and the improvement of the aspect of the skin (removal of the wrinkles, increase of the freshness and of the tenacity of the skin).
Numerous pharmaceutical and cosmetic special products based upon acids of fruits are existing and new ones are appearing regularly.
However the use of these compounds and of compounds closely related to the vitamin A as chemical compositions exhibits the inconvenience of non-negligible or significant secondary effects.
The invention has as its object to cope with the foregoing inconveniences by proposing in particular cosmetic and/or pharmaceutical compositions based upon usual alimentary plants.
For that purpose, the invention proposes a composition characterized in that it comprises a mixture called basic mixture consisting of the liquid extracted from a mixture M of tomatoes and apples, once this spontaneous reaction initiated by the mixture of both plants in crushed form has finished.
According to another characteristic of this composition, the mixture M in addition comprises a gelling or thickening agent and/or an emollient agent.
Preferably this gelling or thickening agent will consist of peaches or persimmons and this emollient agent will consist of cucumbers.
When the mixture M does not comprise any gelling agent or emollient agent, it comprises apples and tomatoes with approximately equal weights.
When the mixture M comprises peaches or persimmons as a gelling or thickening agent or cucumbers as an emollient agent, it comprises between 30 and 35% of peaches or persimmons, between 30 and 35% of apples and about 30% of tomatoes as percentages by weight with respect to the weight of the final mixture (M).
Preferably it comprises between 25 and 30% of peaches or persimmons, between 20 and 25% of apples, between 20 and 25% of tomatoes and between 25 and 30% of cucumbers as percentages by weight with respect to the weight of the final mixture M.
According to another characteristic of the composition according to the invention, one adds a tenderizing or lysing agent to the said basic mixture.
This tenderizing or lysing agent will be more particularly selected in the group constituted by papaw, papain, chimopapain, trypsin, pineapple, latex of the fig tree or pepsin.
The preferred tenderizing or lysing agent of the invention is papaw. In this case one adds about one third by weight of papaw and about two thirds by weight of the said basic mixture.
The compositions according to the invention may in addition contain an acidifying agent. A preferred acidifying agent is lemon juice.
According to another characteristic of the composition according to the invention, one adds an irritating agent to the said basic mixture.
A preferred irritating agent is the cooking water of paprikas or green pimentos.
According to another characteristic of the composition according to the invention, one adds to the said basic mixture a mixture being both skin protecting since comprising substances acting against free radicals such as the vitamin C, the vitamin E, the beta-carotene, and skin-nutritive since comprising vitamins A, B, PP, amino-acids, carbohydrates, purins, fatty acids, calcium and oligo-elements such as iron, copper, manganese, sulphur, phosphorus, diode and possibly phospholipids.
In this alternative embodiment of the invention, the preferred nutritious or nutritive and protecting medium consists of cabbage juice or of the water of cooking, in preferably slightly mineralized water, of cabbages, preferably of green cabbages, possibly in admixture with juice from the cooking water of other plants.
More preferably, the nutritious medium consists of the water of cooking, preferably in slightly mineralized water, either of green cabbages or of a mixture in equal proportions by weight of green cabbages and of green salads with thick leaves such as lettuce.
In this case, one adds to one volume of the composition of the invention without any protecting and nutritive agent, three volumes of the said cooking water.
All these compositions of the invention may be used for the manufacture of a cosmetic and/or pharmaceutical composition intended to promote the care of the skin.
They may also be used for the manufacture of a cosmetic and/or pharmaceutical composition for the treatment of acne, of seborrhea, of psoriasis and of eczema.
In particular the invention proposes a bodily lotion for regenerating and making firmer the skin, which is characterized in that one adds to the said basic mixture or to the basic mixture admixed with a lysing or tenderizing agent, preferably papaw, the nutritious medium containing vitamins A, B, C, D, E, PP, amino-acids, calcium and oligo-elements such as iron, copper, manganese, sulfur, phosphorus, iode etc. and possibly an acidifying agent, preferably lemon juice.
A particularly p

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