Method of making colloid labeled with radionuclide

Details Method of making colloid labeled with radionuclide Method of making colloid labeled with radionuclide

1990-09-11

1991-07-09

Maples, John S.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

252625, A61K 4300, C09K 1104

Patent

active

050304410

ABSTRACT:
A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.

REFERENCES:
patent: Re29066 (1976-12-01), Evans
patent: 4752464 (1988-06-01), Lieberman et al.
Rotmensch et al., "The Developement of .alpha.-Emitting Radionuclide Lead-212", Am. J. Obstet. Gynecol, vol. 160, No. 4, Apr. 1989, pp. 789-797.

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