Method of making antibodies to antigenic epitopes of IGE present

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide

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4351722, 43524027, 53038825, 5303893, 424 858, 514 14, C12P 2108, C12N 1502, C12N 512, C07K 1528

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active

052524671

ABSTRACT:
A method for producing antibodies specific for antigenic associated with the extracellular segment of the domain which anchors immunoglobulins to the B cell membrane is disclosed. The epitopes recognized by the antibodies of the invention are present on IgE-bearing B cells but not basophils or in the secreted, soluble form of IgE.

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