Method of making a rapidly dissolving tablet

Details Method of making a rapidly dissolving tablet Method of making a rapidly dissolving tablet

1994-12-08

1997-06-03

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424484, 424474, 424482, 424499, 264 13, A61K 920, A61K 928, A61K 914, A61K 946

Patent

active

056352107

ABSTRACT:
The present invention comprises a tablet, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Generally, the method of the present invention comprises up to four steps. First, a porous particulate powder which will serve as the tablet support matrix is produced. In the second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In the third step the mixture is formed into a tablet. Finally, in the fourth step, a coating may be applied to the outer surface of the tablet to enhance the intactness and durability of the tablet.

REFERENCES:
patent: 4013784 (1977-03-01), Speiser
patent: 4572832 (1986-02-01), Kigasawa et al.
patent: 5082667 (1992-01-01), Van Scoik
patent: 5178878 (1993-01-01), Wehling et al.
patent: 5215756 (1993-06-01), Gole et al.

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