Method of making a multiwell test plate

Details Method of making a multiwell test plate Method of making a multiwell test plate

1985-06-18

1990-08-14

Warden, Robert J.

Adhesive bonding and miscellaneous chemical manufacture

Methods

Surface bonding and/or assembly therefor

156268, 1563084, 1563096, B32B 3116

Patent

active

049484427

ABSTRACT:
A micro-titre test plate including a thermoplastic incubation tray having an array of a plurality of wells extending therethrough, filter means, and a thermoplastic harvester tray for supporting the filter sheet. The harvester tray has a plurality of apertures therethrough arranged to be registerable with the bottoms of the wells in the incubation tray. To prevent cross-talk between the wells along the filter, the facing surfaces of the harvester tray and incubation tray are provided with mating ridges and grooves circumscribing the juncture of each well and aperture. In one embodiment, the ridges and grooves are thermally bonded to one another to provide a fluid-impervious barrier trapping respective filter disks in the juncture of each well and aperture. In another embodiment, the harvester tray is formed of a pair of apertured, thermoplastic sheets nested with respective thermally bonded grooves and ridges to trap the filter, the harvester tray being not necessarily bonded to the incubation tray.

REFERENCES:
patent: 3111489 (1963-11-01), Getzin
patent: 3540856 (1970-11-01), Rochte et al.
patent: 3540857 (1970-11-01), Martin
patent: 3540858 (1970-11-01), Rochte et al.
patent: 4169751 (1979-10-01), Yen
patent: 4304865 (1981-12-01), O'Brien et al.
patent: 4427415 (1984-01-01), Cleveland
patent: 4493815 (1985-01-01), Fernwood et al.
patent: 4552600 (1985-11-01), Laiewski et al.
Minifold.RTM. Micro-Sample Filtration Manifold, Schleicher & Schull, (1981).

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