Method of making a drug delivery system using hollow fibers

Details Method of making a drug delivery system using hollow fibers Method of making a drug delivery system using hollow fibers

1993-02-19

1996-07-23

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

428396, A61K 970, D01F 1100, D01F 1102, D01F 1106

Patent

active

055387357

ABSTRACT:
The present invention is a timed release drug delivery system using hollow fibers. The drug contents of the voids in the fibers are delivered to the immediate environment of the fiber through the two open ends of each fiber. The present invention further includes a method of using a vacuum chamber for filling the fibers with the drugs to be delivered, and a method to control the manufacturing process of the hollow fibers containing drugs to obtain a certain rate of drug release. The present invention further includes fabrics manufactured from such drug delivery fibers, and articles made from such fabrics, such as vascular grafts and disposable surgical clothing.

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Dunn et al, Proceedings of the 9th Internat'l Symposium on Controlled Release of Bioactive Materials (1982):157-9.

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